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Human Embryonic Stem Cells Derived by Somatic Cell Nuclear Transfer Shoukrat Mitalipov describes how his lab used somatic cell nuclear transfer in human oocytes to create human embryonic stem cells. In this issue's interview, Dr Mitalipov explains that in order to make the technique work, he and his colleagues realized they needed to tweak the protocol by adding caffeine to the culture dish. This PaperClip features the musical theme, "the phoenix - 1st sonata for helena in style of 303" (the phoenix) / CC BY 3.0. Have 5 minutes to learn about cutting-edge research in Cell? Browse our PaperClip archive. Share on facebookShare on emailShare on twitter

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Leading Edge Featured Article  free

Charting Our Decline and Fall  In this Review, Guido Kroemer and colleagues introduce tentative hallmarks to characterize common denominators of aging in different organisms, with special emphasis on mammalian aging. The Hallmarks of Aging Guido Kroemer and colleagues